James Cook vs Christian McCaffrey

“Check out all of Fitz’s top fantasy football draft picks to target >> James Cook (BUF) James Cook led the NFL in rushing yards in 2025 (1,621).”

“James Cook (RB – BUF) has already shown flashes of every skill needed to be the overall RB1: a big receiving season, an 18-touchdown season, and a 1,600-yard rushing season, just never all in the same year.”

“Repeat Seasons It should be more of the same for James Cook and Chase Brown , who saw little change in their offenses this offseason.”

“31 10 21 James Cook 13 5 8 Josh Jacobs 7 15 -8 Saquon Barkley 2 13 -11 Bucky Irving 10 33 -23 In past years, so many top RBs have gotten hurt that the Zero (or hero) RB draft strategies have become popular.”

“I recently gushed about James Cook and Ray Davis as players to target at Underdog at their ADPs .”

“James Cook was picked as the best value on the board at 11th overall, priced almost entirely off last year’s production rather than his upside. The case for a top-three running back season rests on four pillars, and Cook checks every one.”

“James Cook was a no-brainer pick, and it came down to Derrick Henry and Ashton Jeanty for the RB2 slot.”

“The Bills put their money where their mouth is by giving James Cook a ton of money, then followed that up with a bunch of touches (349, to be exact), and brought the rushing title back to Buffalo. James Cook led the NFL in 2025 with 11 games of 80+ rushing yards.”

“Well, so much for all of the regression talk about James Cook last year. Cook crushed all of the haters, improving his stock as the RB6 in fantasy points per game. He led the NFL in rushing yards (1,621) while finishing third in rushing attempts and sixth in rushing touchdowns (tied).”

“James Cook is expected to be more involved in the passing game under new offensive coordinator Pete Carmichael, whose running backs have been heavily involved in the passing attack throughout his coaching history. Cook had a career-high 309 rush attempts in the regular season en route to the NFL rushing title last season, and shifting some of his carries into targets could be a wise move given his excellent receiving skills demonstrated at the NFL level.”

“Unlike Saquon Barkley, who also plays with a quarterback used heavily near the end zone, the Bills do mix in Cook near the end zone, instead of strictly relying on Josh Allen moving the pile. Cook had 14 rushing attempts inside the 5-yard line in 2025 (tied for 8th in the NFL) with 6 touchdowns on those runs.”

“Cook got a new contract last offseason, which was well-earned on the field. He had the best season of his early career, setting career highs in rushing attempts (309), rushing yards (1,621), touches (342), and yards from scrimmage (1,912) to go along with 14 touchdowns.”

“Fantasy Football Research & Advice Fantasy Football Expert Rankings 2026 Fantasy Football Draft Kit Fantasy Football Trade Analyzer Fantasy Football Draft Strategy: Pick 1.04 Players to Consider at 1.04 Fantasy Football Draft Pick These players will likely be available when you make your selection: Ja’Marr Chase (WR – CIN) Puka Nacua (WR – LAR) Jaxon Smith-Njigba (WR – SEA) Christian McCaffrey (RB – SF) It’s fair to assume at least one of Bijan Robinson or Jahmyr Gibbs will be gone, if not both, as they’re the consensus top two picks.”

“Plenty of people have been hurt by fading Christian McCaffrey over the years, and it feels like a dangerous prospect when CMC was the RB1 in PPR points per game, scored 24.5 last year, 2.5 more than Bijan Robinson.”

“McCaffrey fell to 1.95 YAC/A (41st among 51 running backs with at least 90 carries) and -0.54 RYOE/A (47th). Given his age and injury history I’d bet heavily against McCaffrey turning the tides on his declining rush efficiency. Fortunately, he showed absolutely no sign of decline as a receiving threat.”

“McCaffrey is coming off a season where he touched the ball 400+ times and finished all but one week of the season as a top-24 RB. The biggest “if” with CMC is his health, but when he is on the field, he is a fantasy league winner.”

“Now, there are outliers — guys like Christian McCaffrey and Derrick Henry continue to defy the odds and crush it.”

“He's scored 20 TDs twice including last season when he finished as the RB2 overall behind Christian McCaffrey”

“Mason was the RB9 in week’s 1-7 in 2024 while filling in for Christian McCaffrey and found himself as a popular zero RB target a year ago after a trade to the Vikings”

“2 running back in San Francisco behind Christian McCaffrey”

“6 | Diff: +22 Kaelon Black looks to have an early edge to climb into the clear RB2 spot on the 49ers’ depth chart behind Christian McCaffrey , with Jordan James now dealing with a rib fracture.”

“2 Something to note is that while Christian McCaffrey did not reach the total rushing attempts needed to hit this criterion last season, he did have 311 carries, along with 102 receptions, putting his total workload at a similar number.”

“Top-12 Drafted RBs in 2025 RB 2025 ADP 2024 Finish 2025 Games Played Bijan Robinson RB1 RB3 17 Saquon Barkley RB2 RB13 16 Jahmyr Gibbs RB3 RB4 17 Christian McCaffrey RB4 RB1 17 Derrick Henry RB5 RB7 17 Ashton Jeanty RB6 RB12 17 Josh Jacobs RB7 RB15 15 De’Von Achane RB8 RB6 16 Jonathan Taylor RB9 RB2 17 Bucky Irving RB10 RB33 10 Chase Brown RB11 RB8 17 Kyren Williams RB12 RB9 17 2025 RB Health Last season, nine out of 12 top RBs drafted finished as an RB1, resulting in a mostly chalky season at the top for RBs.”

“The last time McCaffrey had over 400 touches in a year, the superstar missed 69.7% of the games over the next two seasons because of injury.”